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Array comparative genomic hybridization identifies high level of PI3K/Akt/mTOR pathway alterations in anal cancer recurrences

Genomic alterations of anal squamous cell carcinoma (ASCC) remain poorly understood due to the rarity of this tumor. Array comparative genomic hybridization and targeted gene sequencing were performed in 49 cases of ASCC. The most frequently altered regions (with a frequency greater than 25%) were 1...

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Detalles Bibliográficos
Autores principales:	Cacheux, Wulfran, Tsantoulis, Petros, Briaux, Adrien, Vacher, Sophie, Mariani, Pascale, Richard‐Molard, Marion, Buecher, Bruno, Richon, Sophie, Jeannot, Emmanuelle, Lazartigues, Julien, Rouleau, Etienne, Mariani, Odette, El Alam, Elsy, Cros, Jérôme, Roman‐Roman, Sergio, Mitry, Emmanuel, Girard, Elodie, Dangles‐Marie, Virginie, Lièvre, Astrid, Bièche, Ivan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2018
Materias:	Cancer Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6051172/ https://www.ncbi.nlm.nih.gov/pubmed/29804324 http://dx.doi.org/10.1002/cam4.1533

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