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Blockade of RBP-J-Mediated Notch Signaling Pathway Exacerbates Cardiac Remodeling after Infarction by Increasing Apoptosis in Mice

BACKGROUND: Ischemic heart disease (IHD) is the major cause of death in patients with cardiovascular disease. Cardiac remodeling is a common pathological change following myocardial infarction (MI), and cardiomyocyte apoptosis plays a key role in this change. Transcription factor recombination signa...

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Detalles Bibliográficos
Autores principales: He, Yanru, Pang, Si, Huang, Jia, Zhu, Kongbo, Tong, Jiayi, Tang, Yaoliang, Ma, Genshan, Chen, Lijuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6051300/
https://www.ncbi.nlm.nih.gov/pubmed/30065940
http://dx.doi.org/10.1155/2018/5207031