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Influence of medications on taste and smell

Medications frequently have chemosensory side effects that can adversely affect compliance with medical treatment regimens. Hundreds of drugs have been reported to induce unpleasant tastes and/or odors as well as altered chemosensations when administered alone or in combination with other medication...

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Autor principal: Schiffman, Susan S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: KeAi Publishing 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6051304/
https://www.ncbi.nlm.nih.gov/pubmed/30035266
http://dx.doi.org/10.1016/j.wjorl.2018.02.005
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author Schiffman, Susan S.
author_facet Schiffman, Susan S.
author_sort Schiffman, Susan S.
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description Medications frequently have chemosensory side effects that can adversely affect compliance with medical treatment regimens. Hundreds of drugs have been reported to induce unpleasant tastes and/or odors as well as altered chemosensations when administered alone or in combination with other medications. Some chemosensory complaints are due to the sensory properties of the drug itself such as aversive bitter and metallic tastes. However, most chemosensory side effects of drugs are due to alterations in the transduction pathways, biochemical targets, enzymes, and transporters by the offending medications. Studies of chemosensory perception in medicated older individuals have found that taste and smell loss is greatest for those consuming the largest number of prescription drugs. There are no standard treatments for drug-induced chemosensory disorders because each drug has unique biological effects. However, there are a few treatment options to ameliorate chemosensory alterations including addition of simulated flavors to food to compensate for losses and to override offending tastes and smells.
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spelling pubmed-60513042018-07-20 Influence of medications on taste and smell Schiffman, Susan S. World J Otorhinolaryngol Head Neck Surg Review Articles and Research Paper Medications frequently have chemosensory side effects that can adversely affect compliance with medical treatment regimens. Hundreds of drugs have been reported to induce unpleasant tastes and/or odors as well as altered chemosensations when administered alone or in combination with other medications. Some chemosensory complaints are due to the sensory properties of the drug itself such as aversive bitter and metallic tastes. However, most chemosensory side effects of drugs are due to alterations in the transduction pathways, biochemical targets, enzymes, and transporters by the offending medications. Studies of chemosensory perception in medicated older individuals have found that taste and smell loss is greatest for those consuming the largest number of prescription drugs. There are no standard treatments for drug-induced chemosensory disorders because each drug has unique biological effects. However, there are a few treatment options to ameliorate chemosensory alterations including addition of simulated flavors to food to compensate for losses and to override offending tastes and smells. KeAi Publishing 2018-03-26 /pmc/articles/PMC6051304/ /pubmed/30035266 http://dx.doi.org/10.1016/j.wjorl.2018.02.005 Text en © 2018 Chinese Medical Association http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Review Articles and Research Paper
Schiffman, Susan S.
Influence of medications on taste and smell
title Influence of medications on taste and smell
title_full Influence of medications on taste and smell
title_fullStr Influence of medications on taste and smell
title_full_unstemmed Influence of medications on taste and smell
title_short Influence of medications on taste and smell
title_sort influence of medications on taste and smell
topic Review Articles and Research Paper
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6051304/
https://www.ncbi.nlm.nih.gov/pubmed/30035266
http://dx.doi.org/10.1016/j.wjorl.2018.02.005
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