Poor Immunogenicity, Not Vaccine Strain Egg Adaptation, May Explain the Low H3N2 Influenza Vaccine Effectiveness in 2012–2013

BACKGROUND: Influenza vaccination aims to prevent infection by influenza virus and reduce associated morbidity and mortality; however, vaccine effectiveness (VE) can be modest, especially for subtype A(H3N2). Low VE has been attributed to mismatches between the vaccine and circulating influenza stra...

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Detalles Bibliográficos
Autores principales: Cobey, Sarah, Gouma, Sigrid, Parkhouse, Kaela, Chambers, Benjamin S, Ertl, Hildegund C, Schmader, Kenneth E, Halpin, Rebecca A, Lin, Xudong, Stockwell, Timothy B, Das, Suman R, Landon, Emily, Tesic, Vera, Youngster, Ilan, Pinsky, Benjamin A, Wentworth, David E, Hensley, Scott E, Grad, Yonatan H
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Articles and Commentary
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6051447/
https://www.ncbi.nlm.nih.gov/pubmed/29471464
http://dx.doi.org/10.1093/cid/ciy097

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