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A Review of the Mechanism of Antagonism of N-methyl-D-aspartate Receptor by Ketamine in Treatment-resistant Depression

The biochemical processes involved in depression go beyond serotonin, norepinephrine, and dopamine. The N-methyl-D-aspartate (NMDA) receptor has a major role in the neurophysiology of depression. Ketamine, one of the prototypical NMDA antagonists, works rapidly in controlling depressive symptoms, in...

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Detalles Bibliográficos
Autores principales: Sattar, Yasar, Wilson, John, Khan, Ali M, Adnan, Mahwish, Azzopardi Larios, Daniel, Shrestha, Shristi, Rahman, Quazi, Mansuri, Zeeshan, Hassan, Ali, Patel, Nirav B, Tariq, Nargis, Latchana, Sharaad, Lopez Pantoja, Stefany C, Vargas, Sadiasept, Shaikh, Naveed A, Syed, Fawaduzzaman, Mittal, Daaman, Rumesa, Fatima
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6051558/
https://www.ncbi.nlm.nih.gov/pubmed/30034974
http://dx.doi.org/10.7759/cureus.2652