Deletion of Nkx2-5 in trabecular myocardium reveals the developmental origins of pathological heterogeneity associated with ventricular non-compaction cardiomyopathy

Left ventricular non-compaction (LVNC) is a rare cardiomyopathy associated with a hypertrabeculated phenotype and a large spectrum of symptoms. It is still unclear whether LVNC results from a defect of ventricular trabeculae development and the mechanistic basis that underlies the varying severity o...

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Detalles Bibliográficos
Autores principales: Choquet, Caroline, Nguyen, Thi Hong Minh, Sicard, Pierre, Buttigieg, Emeline, Tran, Thi Thom, Kober, Frank, Varlet, Isabelle, Sturny, Rachel, Costa, Mauro W., Harvey, Richard P., Nguyen, Catherine, Rihet, Pascal, Richard, Sylvain, Bernard, Monique, Kelly, Robert G., Lalevée, Nathalie, Miquerol, Lucile
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6051668/
https://www.ncbi.nlm.nih.gov/pubmed/29979676
http://dx.doi.org/10.1371/journal.pgen.1007502

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