MSH6 and PMS2 germ-line pathogenic variants implicated in Lynch syndrome are associated with breast cancer

PURPOSE: An association of Lynch syndrome (LS) with breast cancer has been long suspected; however, there have been insufficient data to address this question for each of the LS genes individually. METHODS: We conducted a retrospective review of personal and family history in 423 women with pathogen...

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Detalles Bibliográficos
Autores principales: Roberts, Maegan E, Jackson, Sarah A, Susswein, Lisa R, Zeinomar, Nur, Ma, Xinran, Marshall, Megan L, Stettner, Amy R, Milewski, Becky, Xu, Zhixiong, Solomon, Benjamin D, Terry, Mary Beth, Hruska, Kathleen S, Klein, Rachel T, Chung, Wendy K
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group US 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6051923/
https://www.ncbi.nlm.nih.gov/pubmed/29345684
http://dx.doi.org/10.1038/gim.2017.254

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