A complex of C9ORF72 and p62 uses arginine methylation to eliminate stress granules by autophagy

Mutations in proteins like FUS which cause Amyotrophic Lateral Sclerosis (ALS) result in the aberrant formation of stress granules while ALS-linked mutations in other proteins impede elimination of stress granules. Repeat expansions in C9ORF72, the major cause of ALS, reduce C9ORF72 levels but how t...

Descripción completa

Detalles Bibliográficos
Autores principales: Chitiprolu, Maneka, Jagow, Chantal, Tremblay, Veronique, Bondy-Chorney, Emma, Paris, Geneviève, Savard, Alexandre, Palidwor, Gareth, Barry, Francesca A., Zinman, Lorne, Keith, Julia, Rogaeva, Ekaterina, Robertson, Janice, Lavallée-Adam, Mathieu, Woulfe, John, Couture, Jean-François, Côté, Jocelyn, Gibbings, Derrick
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6052026/
https://www.ncbi.nlm.nih.gov/pubmed/30022074
http://dx.doi.org/10.1038/s41467-018-05273-7

Ejemplares similares

Ejemplares similares