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Renoprotective effects of a factor Xa inhibitor: fusion of basic research and a database analysis
Renal tubulointerstitial injury, an inflammation-associated condition, is a major cause of chronic kidney disease (CKD). Levels of activated factor X (FXa), a blood coagulation factor, are increased in various inflammatory diseases. Therefore, we investigated the protective effects of an FXa inhibit...
Autores principales: | Horinouchi, Yuya, Ikeda, Yasumasa, Fukushima, Keijo, Imanishi, Masaki, Hamano, Hirofumi, Izawa-Ishizawa, Yuki, Zamami, Yoshito, Takechi, Kenshi, Miyamoto, Licht, Fujino, Hiromichi, Ishizawa, Keisuke, Tsuchiya, Koichiro, Tamaki, Toshiaki |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6052035/ https://www.ncbi.nlm.nih.gov/pubmed/30022146 http://dx.doi.org/10.1038/s41598-018-29008-2 |
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