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Developmental arrest in Drosophila melanogaster caused by mitochondrial DNA replication defects cannot be rescued by the alternative oxidase

The xenotopic expression of the alternative oxidase AOX from the tunicate Ciona intestinalis in diverse models of human disease partially alleviates the phenotypic effects of mitochondrial respiratory chain defects. AOX is a non-proton pumping, mitochondrial inner membrane-bound, single-subunit enzy...

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Detalles Bibliográficos
Autores principales:	Rodrigues, Ana Paula C., Camargo, André F., Andjelković, Ana, Jacobs, Howard T., Oliveira, Marcos T.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6052043/ https://www.ncbi.nlm.nih.gov/pubmed/30022066 http://dx.doi.org/10.1038/s41598-018-29150-x

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