The concerted roles of FANCM and Rad52 in the protection of common fragile sites

Common fragile sites (CFSs) are prone to chromosomal breakage and are hotspots for chromosomal rearrangements in cancer cells. We uncovered a novel function of Fanconi anemia (FA) protein FANCM in the protection of CFSs that is independent of the FA core complex and the FANCI–FANCD2 complex. FANCM,...

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Detalles Bibliográficos
Autores principales: Wang, Hailong, Li, Shibo, Oaks, Joshua, Ren, Jianping, Li, Lei, Wu, Xiaohua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6052092/
https://www.ncbi.nlm.nih.gov/pubmed/30022024
http://dx.doi.org/10.1038/s41467-018-05066-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6052092/
https://www.ncbi.nlm.nih.gov/pubmed/30022024
http://dx.doi.org/10.1038/s41467-018-05066-y

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