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Single-cell trajectory analysis of human homogenous neurons carrying a rare RELN variant

Reelin is a protein encoded by the RELN gene that controls neuronal migration in the developing brain. Human genetic studies suggest that rare RELN variants confer susceptibility to mental disorders such as schizophrenia. However, it remains unknown what effects rare RELN variants have on human neur...

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Detalles Bibliográficos
Autores principales: Arioka, Yuko, Shishido, Emiko, Kubo, Hisako, Kushima, Itaru, Yoshimi, Akira, Kimura, Hiroki, Ishizuka, Kanako, Aleksic, Branko, Maeda, Takuji, Ishikawa, Mitsuru, Kuzumaki, Naoko, Okano, Hideyuki, Mori, Daisuke, Ozaki, Norio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6052151/
https://www.ncbi.nlm.nih.gov/pubmed/30022058
http://dx.doi.org/10.1038/s41398-018-0177-8