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Combination of PI3K/Akt Pathway Inhibition and Plk1 Depletion Can Enhance Chemosensitivity to Gemcitabine in Pancreatic Carcinoma

The prognosis of pancreatic cancer (PC) remains pessimistic because of the difficulty in early diagnosis as well as the little advance in chemotherapy. Although being the first-line chemotherapy drug for PC at present, gemcitabine still has some disadvantages, such as low drug sensitivity and signif...

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Detalles Bibliográficos
Autores principales:	Mao, Yonghuan, Xi, Ling, Li, Quan, Wang, Sheng, Cai, Zeling, Zhang, Xinhua, Yu, Chunzhao
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Neoplasia Press 2018
Materias:	Original article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6052177/ https://www.ncbi.nlm.nih.gov/pubmed/29753186 http://dx.doi.org/10.1016/j.tranon.2018.04.011

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