Control of Heterologous Simian Immunodeficiency Virus SIV(smE660) Infection by DNA and Protein Coimmunization Regimens Combined with Different Toll-Like-Receptor-4-Based Adjuvants in Macaques

We developed a method of simultaneous vaccination with DNA and protein resulting in robust and durable cellular and humoral immune responses with efficient dissemination to mucosal sites and protection against simian immunodeficiency virus (SIV) infection. To further optimize the DNA-protein coimmun...

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Detalles Bibliográficos
Autores principales: Singh, Shakti, Ramírez-Salazar, Eric G., Doueiri, Rami, Valentin, Antonio, Rosati, Margherita, Hu, Xintao, Keele, Brandon F., Shen, Xiaoying, Tomaras, Georgia D., Ferrari, Guido, LaBranche, Celia, Montefiori, David C., Das, Jishnu, Alter, Galit, Trinh, Hung V., Hamlin, Christopher, Rao, Mangala, Dayton, Frances, Bear, Jenifer, Chowdhury, Bhabadeb, Alicea, Candido, Lifson, Jeffrey D., Broderick, Kate E., Sardesai, Niranjan Y., Sivananthan, Sandra J., Fox, Christopher B., Reed, Steven G., Venzon, David J., Hirsch, Vanessa M., Pavlakis, George N., Felber, Barbara K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2018
Materias:
Vaccines and Antiviral Agents
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6052320/
https://www.ncbi.nlm.nih.gov/pubmed/29793957
http://dx.doi.org/10.1128/JVI.00281-18

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