Specnuezhenide Decreases Interleukin-1β-Induced Inflammation in Rat Chondrocytes and Reduces Joint Destruction in Osteoarthritic Rats

As a chronic disease, osteoarthritis (OA) leads to the degradation of both cartilage and subchondral bone, its development being mediated by proinflammatory cytokines like interleukin-1β. In the present study, the anti-inflammatory effect of specnuezhenide (SPN) in OA and its underlying mechanism we...

Descripción completa

Detalles Bibliográficos
Autores principales: Ma, Chiyuan, Zhou, Xiaopeng, Xu, Kai, Wang, Linyan, Yang, Yute, Wang, Wei, Liu, An, Ran, Jisheng, Yan, Shigui, Wu, Haobo, Wu, Lidong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6052343/
https://www.ncbi.nlm.nih.gov/pubmed/30050432
http://dx.doi.org/10.3389/fphar.2018.00700

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6052343/
https://www.ncbi.nlm.nih.gov/pubmed/30050432
http://dx.doi.org/10.3389/fphar.2018.00700

Ejemplares similares