Impaired AMPA signaling and cytoskeletal alterations induce early synaptic dysfunction in a mouse model of Alzheimer's disease

Alzheimer's disease (AD) is a devastating neurodegenerative disorder that impairs memory and causes cognitive and psychiatric deficits. New evidences indicate that AD is conceptualized as a disease of synaptic failure, although the molecular and cellular mechanisms underlying these defects rema...

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Detalles Bibliográficos
Autores principales: Baglietto‐Vargas, David, Prieto, Gilberto Aleph, Limon, Agenor, Forner, Stefania, Rodriguez‐Ortiz, Carlos J., Ikemura, Kenji, Ager, Rahasson R., Medeiros, Rodrigo, Trujillo‐Estrada, Laura, Martini, Alessandra C., Kitazawa, Masashi, Davila, Jose C., Cotman, Carl W., Gutierrez, Antonia, LaFerla, Frank M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6052400/
https://www.ncbi.nlm.nih.gov/pubmed/29877034
http://dx.doi.org/10.1111/acel.12791

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