Comparative transcriptomics across 14 Drosophila species reveals signatures of longevity

Lifespan varies dramatically among species, but the biological basis is not well understood. Previous studies in model organisms revealed the importance of nutrient sensing, mTOR, NAD/sirtuins, and insulin/IGF1 signaling in lifespan control. By studying life‐history traits and transcriptomes of 14 D...

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Detalles Bibliográficos
Autores principales: Ma, Siming, Avanesov, Andrei S., Porter, Emily, Lee, Byung Cheon, Mariotti, Marco, Zemskaya, Nadezhda, Guigo, Roderic, Moskalev, Alexey A., Gladyshev, Vadim N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6052463/
https://www.ncbi.nlm.nih.gov/pubmed/29671950
http://dx.doi.org/10.1111/acel.12740

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6052463/
https://www.ncbi.nlm.nih.gov/pubmed/29671950
http://dx.doi.org/10.1111/acel.12740

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