SIRT4 is essential for metabolic control and meiotic structure during mouse oocyte maturation

SIRT4 modulates energy homeostasis in multiple cell types and tissues. However, its role in meiotic oocytes remains unknown. Here, we report that mouse oocytes overexpressing SIRT4 are unable to completely progress through meiosis, showing the inadequate mitochondrial redistribution, lowered ATP con...

Descripción completa

Detalles Bibliográficos
Autores principales: Zeng, Juan, Jiang, Manxi, Wu, Xinghan, Diao, Feiyang, Qiu, Danhong, Hou, Xiaojing, Wang, Haichao, Li, Ling, Li, Chunling, Ge, Juan, Liu, Jiayin, Ou, Xianghong, Wang, Qiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6052465/
https://www.ncbi.nlm.nih.gov/pubmed/29845740
http://dx.doi.org/10.1111/acel.12789

Ejemplares similares

Ejemplares similares