HTRA1, an age‐related macular degeneration protease, processes extracellular matrix proteins EFEMP1 and TSP1

High‐temperature requirement protein A1 (HTRA1) is a serine protease secreted by a number of tissues including retinal pigment epithelium (RPE). A promoter variant of the gene encoding HTRA1 is part of a mutant allele that causes increased HTRA1 expression and contributed to age‐related macular dege...

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Detalles Bibliográficos
Autores principales: Lin, Michael K., Yang, Jin, Hsu, Chun Wei, Gore, Anuradha, Bassuk, Alexander G., Brown, Lewis M., Colligan, Ryan, Sengillo, Jesse D., Mahajan, Vinit B., Tsang, Stephen H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6052470/
https://www.ncbi.nlm.nih.gov/pubmed/29730901
http://dx.doi.org/10.1111/acel.12710

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6052470/
https://www.ncbi.nlm.nih.gov/pubmed/29730901
http://dx.doi.org/10.1111/acel.12710

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