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Downregulation of miR-133a-3p promotes prostate cancer bone metastasis via activating PI3K/AKT signaling

BACKGROUND: Bone metastasis is a leading cause of morbidity and mortality in advanced prostate cancer (PCa). Downexpression of miR-133a-3p has been found to contribute to the progression, recurrence and distant metastasis in PCa. However, clinical significance of miR-133a-3p in bone metastasis of PC...

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Detalles Bibliográficos
Autores principales: Tang, Yubo, Pan, Jincheng, Huang, Shuai, Peng, Xinsheng, Zou, Xuenong, Luo, Yongxiang, Ren, Dong, Zhang, Xin, Li, Ronggang, He, Peiheng, Wa, Qingde
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6052526/
https://www.ncbi.nlm.nih.gov/pubmed/30021600
http://dx.doi.org/10.1186/s13046-018-0813-4

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