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Beneficial Effect of a Selective Adenosine A(2A) Receptor Antagonist in the APPswe/PS1dE9 Mouse Model of Alzheimer’s Disease

Consumption of caffeine, a non-selective adenosine A(2A) receptor (A(2A)R) antagonist, reduces the risk of developing Alzheimer’s disease (AD) and mitigates both amyloid and Tau lesions in transgenic mouse models of the disease. While short-term treatment with A(2A)R antagonists have been shown to a...

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Detalles Bibliográficos
Autores principales:	Faivre, Emilie, Coelho, Joana E., Zornbach, Katja, Malik, Enas, Baqi, Younis, Schneider, Marion, Cellai, Lucrezia, Carvalho, Kevin, Sebda, Shéhérazade, Figeac, Martin, Eddarkaoui, Sabiha, Caillierez, Raphaëlle, Chern, Yijuang, Heneka, Michael, Sergeant, Nicolas, Müller, Christa E., Halle, Annett, Buée, Luc, Lopes, Luisa V., Blum, David
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2018
Materias:	Neuroscience
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6052540/ https://www.ncbi.nlm.nih.gov/pubmed/30050407 http://dx.doi.org/10.3389/fnmol.2018.00235

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