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Increased expression of the Cbl family of E3 ubiquitin ligases decreases Interleukin-2 production in a rat model of peripheral neuropathy

BACKGROUND: Interleukin 2 (IL-2) influences the development and severity of pain due to its antinociceptive and immunomodulatory effects. Its production is influenced by the increased expression of c-Cbl (Casitas B-lineage lymphoma proto-oncogene) and Cbl-b E3 ubiquitin ligases. We evaluated the eff...

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Detalles Bibliográficos
Autores principales:	Jeong, Ji Seon, Kim, Ha Yeon, Shin, Byung Seop, Lee, Ae Ryoung, Yoon, Ji Hyun, Hahm, Tae Soo, Lee, Ja Eun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2018
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6052554/ https://www.ncbi.nlm.nih.gov/pubmed/30021515 http://dx.doi.org/10.1186/s12871-018-0555-z

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