An inhibitor of 11-β hydroxysteroid dehydrogenase type 1 (PF915275) alleviates nonylphenol-induced hyperadrenalism and adiposity in rat and human cells

BACKGROUND: Nonylphenol (NP) is an environmental endocrine-disrupting chemical (EDC) detected in human cord blood and milk. NP exposure in developmental periods results in hyperadrenalism and increasing 11β-hydroxysteroid dehydrogenase I (11β-HSD1) activity in an adult rat model. Alleviating 11β-HSD...

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Detalles Bibliográficos
Autores principales: Chang, Ling-Ling, Wun, Wan-Song Alfred, Wang, Paulus S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6052566/
https://www.ncbi.nlm.nih.gov/pubmed/30021644
http://dx.doi.org/10.1186/s40360-018-0235-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6052566/
https://www.ncbi.nlm.nih.gov/pubmed/30021644
http://dx.doi.org/10.1186/s40360-018-0235-0

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