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Phosphatidylinositol 3-kinase-δ (PI3K-δ) is a potential therapeutic target in adult T-cell leukemia-lymphoma

The prognosis of adult T-cell leukemia-lymphoma (ATL) remains very poor, and there is an urgent clinical need to investigate novel therapies for ATL. The expression of phosphatidylinositol 3-kinase-δ (PI3k-δ) is normally restricted to hematopoietic cells and is known as a key determinant of cell sur...

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Detalles Bibliográficos
Autores principales: Katsuya, Hiroo, Cook, Lucy B. M., Rowan, Aileen G., Satou, Yorifumi, Taylor, Graham P., Bangham, Charles R. M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6052569/
https://www.ncbi.nlm.nih.gov/pubmed/30034808
http://dx.doi.org/10.1186/s40364-018-0138-7

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