Bone marrow derived mesenchymal stem cells ameliorate inflammatory response in an in vitro model of familial hemophagocytic lymphohistiocytosis 2

BACKGROUND: Familial hemophagocytic lymphohistiocytosis 2 (FHL2) is the most common familial type of hemophagocytic lymphohistiocytosis with immune dysregulation. FHL2 patients have mutations in the perforin gene which cause overactivation and proliferation of cytotoxic T lymphocytes and natural kil...

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Detalles Bibliográficos
Autores principales: Sevim, Handan, Kocaefe, Yusuf Çetin, Onur, Mehmet Ali, Uçkan-Çetinkaya, Duygu, Gürpınar, Özer Aylin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6052587/
https://www.ncbi.nlm.nih.gov/pubmed/30021624
http://dx.doi.org/10.1186/s13287-018-0941-y

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