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Formulation and evaluation of pH-sensitive rutin nanospheres against colon carcinoma using HCT-116 cell line
The objective of this study was to target rutin, in a more solubilized form, to the colon aiming at treatment of colon carcinoma. pH sensitive nanospheres were prepared by the nanoprecipitation technique employing Eudragit S100. Different drug: polymer ratios as well as different concentrations of t...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier
2017
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6052648/ https://www.ncbi.nlm.nih.gov/pubmed/30034879 http://dx.doi.org/10.1016/j.jare.2017.10.003 |