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Expanding TAVI to Low and Intermediate Risk Patients
TAVI has become the standard treatment in patients at increased surgical risk and is increasingly being performed in patients at intermediate to low surgical risk. While non-inferiority has been demonstrated in intermediate risk patients, several challenges—particularly with regard to valve durabili...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6052659/ https://www.ncbi.nlm.nih.gov/pubmed/30050909 http://dx.doi.org/10.3389/fcvm.2018.00092 |
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author | Voigtländer, Lisa Seiffert, Moritz |
author_facet | Voigtländer, Lisa Seiffert, Moritz |
author_sort | Voigtländer, Lisa |
collection | PubMed |
description | TAVI has become the standard treatment in patients at increased surgical risk and is increasingly being performed in patients at intermediate to low surgical risk. While non-inferiority has been demonstrated in intermediate risk patients, several challenges—particularly with regard to valve durability—need to be addressed before expansion to lower risk and younger patients can be recommended on a broad basis. Current trends, trials results, and remaining challenges are summarized and discussed in the light of updated treatment guidelines. |
format | Online Article Text |
id | pubmed-6052659 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2018 |
publisher | Frontiers Media S.A. |
record_format | MEDLINE/PubMed |
spelling | pubmed-60526592018-07-26 Expanding TAVI to Low and Intermediate Risk Patients Voigtländer, Lisa Seiffert, Moritz Front Cardiovasc Med Cardiovascular Medicine TAVI has become the standard treatment in patients at increased surgical risk and is increasingly being performed in patients at intermediate to low surgical risk. While non-inferiority has been demonstrated in intermediate risk patients, several challenges—particularly with regard to valve durability—need to be addressed before expansion to lower risk and younger patients can be recommended on a broad basis. Current trends, trials results, and remaining challenges are summarized and discussed in the light of updated treatment guidelines. Frontiers Media S.A. 2018-07-12 /pmc/articles/PMC6052659/ /pubmed/30050909 http://dx.doi.org/10.3389/fcvm.2018.00092 Text en Copyright © 2018 Voigtländer and Seiffert. http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms. |
spellingShingle | Cardiovascular Medicine Voigtländer, Lisa Seiffert, Moritz Expanding TAVI to Low and Intermediate Risk Patients |
title | Expanding TAVI to Low and Intermediate Risk Patients |
title_full | Expanding TAVI to Low and Intermediate Risk Patients |
title_fullStr | Expanding TAVI to Low and Intermediate Risk Patients |
title_full_unstemmed | Expanding TAVI to Low and Intermediate Risk Patients |
title_short | Expanding TAVI to Low and Intermediate Risk Patients |
title_sort | expanding tavi to low and intermediate risk patients |
topic | Cardiovascular Medicine |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6052659/ https://www.ncbi.nlm.nih.gov/pubmed/30050909 http://dx.doi.org/10.3389/fcvm.2018.00092 |
work_keys_str_mv | AT voigtlanderlisa expandingtavitolowandintermediateriskpatients AT seiffertmoritz expandingtavitolowandintermediateriskpatients |