Epithelial mesenchymal transition (EMT): a universal process in lung diseases with implications for cystic fibrosis pathophysiology

Cystic Fibrosis (CF) is a genetic disorder that arises due to mutations in the Cystic Fibrosis Transmembrane Conductance Regulator gene, which encodes for a protein responsible for ion transport out of epithelial cells. This leads to a disruption in transepithelial Cl-, Na + and HCO(3)− ion transpor...

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Detalles Bibliográficos
Autores principales: Rout-Pitt, Nathan, Farrow, Nigel, Parsons, David, Donnelley, Martin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6052671/
https://www.ncbi.nlm.nih.gov/pubmed/30021582
http://dx.doi.org/10.1186/s12931-018-0834-8

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