Loss of T-cell protein tyrosine phosphatase in the intestinal epithelium promotes local inflammation by increasing colonic stem cell proliferation

T-cell protein tyrosine phosphatase (TC-PTP) has a critical role in the development of the immune system and has been identified as a negative regulator of inflammation. Single-nucleotide polymorphisms in the TC-PTP locus have been associated with increased susceptibility to inflammatory bowel disea...

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Detalles Bibliográficos
Autores principales: Bussières-Marmen, Stéphanie, Vinette, Valérie, Gungabeesoon, Jeremy, Aubry, Isabelle, Pérez-Quintero, Luis Alberto, Tremblay, Michel L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6052838/
https://www.ncbi.nlm.nih.gov/pubmed/28287113
http://dx.doi.org/10.1038/cmi.2016.72

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