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The actin remodeling protein cofilin is crucial for thymic αβ but not γδ T-cell development

Cofilin is an essential actin remodeling protein promoting depolymerization and severing of actin filaments. To address the relevance of cofilin for the development and function of T cells in vivo, we generated knock-in mice in which T-cell–specific nonfunctional (nf) cofilin was expressed instead o...

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Detalles Bibliográficos
Autores principales:	Seeland, Isabel, Xiong, Ying, Orlik, Christian, Deibel, Daniel, Prokosch, Sandra, Küblbeck, Günter, Jahraus, Beate, De Stefano, Daniela, Moos, Sonja, Kurschus, Florian C., Arnold, Bernd, Samstag, Yvonne
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2018
Materias:	Short Reports
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6053251/ https://www.ncbi.nlm.nih.gov/pubmed/29985916 http://dx.doi.org/10.1371/journal.pbio.2005380

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