Embryonic germ cell extracts erase imprinted genes and improve the efficiency of induced pluripotent stem cells

Patient-specific induced pluripotent stem cells (iPSCs) have the potential to be useful in the treatment of human diseases. While prior studies have reported multiple methods to generate iPSCs, DNA methylation continues to limit the totipotency and reprogramming efficiency of iPSCs. Here, we first s...

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Detalles Bibliográficos
Autores principales: Hu, Jing, Zhao, Qiaoshi, Feng, Yukuan, Li, Na, Gu, Yanli, Sun, Ruizhen, Duan, Lian, Wu, Yanshuang, Shan, Zhiyan, Lei, Lei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6053380/
https://www.ncbi.nlm.nih.gov/pubmed/30026469
http://dx.doi.org/10.1038/s41598-018-29339-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6053380/
https://www.ncbi.nlm.nih.gov/pubmed/30026469
http://dx.doi.org/10.1038/s41598-018-29339-0

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