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Embryonic germ cell extracts erase imprinted genes and improve the efficiency of induced pluripotent stem cells
Patient-specific induced pluripotent stem cells (iPSCs) have the potential to be useful in the treatment of human diseases. While prior studies have reported multiple methods to generate iPSCs, DNA methylation continues to limit the totipotency and reprogramming efficiency of iPSCs. Here, we first s...
Autores principales: | Hu, Jing, Zhao, Qiaoshi, Feng, Yukuan, Li, Na, Gu, Yanli, Sun, Ruizhen, Duan, Lian, Wu, Yanshuang, Shan, Zhiyan, Lei, Lei |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6053380/ https://www.ncbi.nlm.nih.gov/pubmed/30026469 http://dx.doi.org/10.1038/s41598-018-29339-0 |
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