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Mapping the sensing spots of aerolysin for single oligonucleotides analysis

Nanopore sensing is a powerful single-molecule method for DNA and protein sequencing. Recent studies have demonstrated that aerolysin exhibits a high sensitivity for single-molecule detection. However, the lack of the atomic resolution structure of aerolysin pore has hindered the understanding of it...

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Detalles Bibliográficos
Autores principales: Cao, Chan, Li, Meng-Yin, Cirauqui, Nuria, Wang, Ya-Qian, Dal Peraro, Matteo, Tian, He, Long, Yi-Tao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6053387/
https://www.ncbi.nlm.nih.gov/pubmed/30026547
http://dx.doi.org/10.1038/s41467-018-05108-5