Neuropil contraction in relation to Complement C4 gene copy numbers in independent cohorts of adolescent-onset and young adult-onset schizophrenia patients–a pilot study

A recent report suggested Complement 4 (C4A) gene copy numbers (GCN) as risk factors for schizophrenia. Rodent model showed association of C4 with synaptic pruning suggesting its pathophysiological significance (Sekar, A. et al. (2016)). We, therefore, predicted that C4A GCN would be positively corr...

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Detalles Bibliográficos
Autores principales: Prasad, Konasale M., Chowdari, Kodavali V., D’Aiuto, Leonardo A., Iyengar, Satish, Stanley, Jeffrey A., Nimgaonkar, Vishwajit L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6053402/
https://www.ncbi.nlm.nih.gov/pubmed/30026462
http://dx.doi.org/10.1038/s41398-018-0181-z

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