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Runx1-Stat3 signaling regulates the epithelial stem cells in continuously growing incisors

Rodent incisors grow permanently and the homeostasis of enamel production is maintained by a continuous supply of epithelial progenitors from putative stem cells in the cervical loop. We herein report that Runx1 regulates the Lgr5-expressing epithelial stem cells and their subsequent continuous diff...

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Detalles Bibliográficos
Autores principales: Sarper, Safiye E., Inubushi, Toshihiro, Kurosaka, Hiroshi, Ono Minagi, Hitomi, Kuremoto, Koh-ichi, Sakai, Takayoshi, Taniuchi, Ichiro, Yamashiro, Takashi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6053438/
https://www.ncbi.nlm.nih.gov/pubmed/30026553
http://dx.doi.org/10.1038/s41598-018-29317-6