Cellular stress induces erythrocyte assembly on intravascular von Willebrand factor strings and promotes microangiopathy

Microangiopathy with subsequent organ damage represents a major complication in several diseases. The mechanisms leading to microvascular occlusion include von Willebrand factor (VWF), notably the formation of ultra-large von Willebrand factor fibers (ULVWFs) and platelet aggregation. To date, the c...

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Detalles Bibliográficos
Autores principales: Nicolay, Jan P., Thorn, Verena, Daniel, Christoph, Amann, Kerstin, Siraskar, Balasaheb, Lang, Florian, Hillgruber, Carina, Goerge, Tobias, Hoffmann, Stefan, Gorzelanny, Christian, Huck, Volker, Mess, Christian, Obser, Tobias, Schneppenheim, Reinhard, Fleming, Ingrid, Schneider, Matthias F., Schneider, Stefan W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6053440/
https://www.ncbi.nlm.nih.gov/pubmed/30026593
http://dx.doi.org/10.1038/s41598-018-28961-2

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