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Maternal betaine supplementation affects fetal growth and lipid metabolism of high-fat fed mice in a temporal-specific manner

BACKGROUND/OBJECTIVES: Maternal obesity increases the risk of gestational diabetes mellitus (GDM), which results in fetal overgrowth and long-lasting metabolic dysfunctioning in the offspring. Previous studies show that maternal choline supplementation normalizes fetal growth and adiposity of progen...

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Detalles Bibliográficos
Autores principales: Joselit, Yaelle, Nanobashvili, Khatia, Jack-Roberts, Chauntelle, Greenwald, Esther, Malysheva, Olga V, Caudill, Marie A, Saxena, Anjana, Jiang, Xinyin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6053452/
https://www.ncbi.nlm.nih.gov/pubmed/30026535
http://dx.doi.org/10.1038/s41387-018-0035-z