Contribution of the gp120 V3 loop to envelope glycoprotein trimer stability in primate immunodeficiency viruses

The V3 loop of the human immunodeficiency virus type 1 (HIV-1) gp120 exterior envelope glycoprotein (Env) becomes exposed after CD4 binding and contacts the coreceptor to mediate viral entry. Prior to CD4 engagement, a hydrophobic patch located at the tip of the V3 loop stabilizes the non-covalent a...

Descripción completa

Detalles Bibliográficos
Autores principales: Bowder, Dane, Hollingsead, Haley, Durst, Kate, Hu, Duoyi, Wei, Wenzhong, Wiggins, Joshua, Medjahed, Halima, Finzi, Andrés, Sodroski, Joseph, Xiang, Shi-Hua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Academic Press 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6053598/
https://www.ncbi.nlm.nih.gov/pubmed/29936340
http://dx.doi.org/10.1016/j.virol.2018.06.005

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6053598/
https://www.ncbi.nlm.nih.gov/pubmed/29936340
http://dx.doi.org/10.1016/j.virol.2018.06.005

Ejemplares similares