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Contribution of the gp120 V3 loop to envelope glycoprotein trimer stability in primate immunodeficiency viruses
The V3 loop of the human immunodeficiency virus type 1 (HIV-1) gp120 exterior envelope glycoprotein (Env) becomes exposed after CD4 binding and contacts the coreceptor to mediate viral entry. Prior to CD4 engagement, a hydrophobic patch located at the tip of the V3 loop stabilizes the non-covalent a...
| Autores principales: | , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Academic Press
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6053598/ https://www.ncbi.nlm.nih.gov/pubmed/29936340 http://dx.doi.org/10.1016/j.virol.2018.06.005 |