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The role of the jaw subdomain of peptidoglycan glycosyltransferases for lipid II polymerization
Bacterial peptidoglycan glycosyltransferases (PGT) catalyse the essential polymerization of lipid II into linear glycan chains required for peptidoglycan biosynthesis. The PGT domain is composed of a large head subdomain and a smaller jaw subdomain and can be potently inhibited by the antibiotic moe...
Autores principales: | Punekar, Avinash S., Samsudin, Firdaus, Lloyd, Adrian J., Dowson, Christopher G., Scott, David J., Khalid, Syma, Roper, David I. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6053601/ https://www.ncbi.nlm.nih.gov/pubmed/30046666 http://dx.doi.org/10.1016/j.tcsw.2018.06.002 |
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