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Novel application of the matched case–control design to compare food supply chains during an Escherichia coli O157 outbreak, United Kingdom, 2016

There is a need for innovative methods to investigate outbreaks of food-borne infection linked to produce with a complex distribution network. The investigation of a large outbreak of Escherichia coli O157 PT34 infection in the United Kingdom in 2016 indicated that catering venues associated with mu...

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Autores principales: Inns, Thomas, Cleary, Paul, Bundle, Nick, Foulkes, Sarah, Sharp, Ashley, Utsi, Lara, McBrien, Chris, Teagle, Rehman, Waldram, Alison, Williams, Chris, McCann, Cathy, Smith, Rob, Saleh, Sepeedeh, McCarthy, Noel, Vivancos, Roberto, Hawker, Jeremy, Decraene, Valerie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: European Centre for Disease Prevention and Control (ECDC) 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6053626/
https://www.ncbi.nlm.nih.gov/pubmed/29741154
http://dx.doi.org/10.2807/1560-7917.ES.2018.23.18.17-00195
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author Inns, Thomas
Cleary, Paul
Bundle, Nick
Foulkes, Sarah
Sharp, Ashley
Utsi, Lara
McBrien, Chris
Teagle, Rehman
Waldram, Alison
Williams, Chris
McCann, Cathy
Smith, Rob
Saleh, Sepeedeh
McCarthy, Noel
Vivancos, Roberto
Hawker, Jeremy
Decraene, Valerie
author_facet Inns, Thomas
Cleary, Paul
Bundle, Nick
Foulkes, Sarah
Sharp, Ashley
Utsi, Lara
McBrien, Chris
Teagle, Rehman
Waldram, Alison
Williams, Chris
McCann, Cathy
Smith, Rob
Saleh, Sepeedeh
McCarthy, Noel
Vivancos, Roberto
Hawker, Jeremy
Decraene, Valerie
author_sort Inns, Thomas
collection PubMed
description There is a need for innovative methods to investigate outbreaks of food-borne infection linked to produce with a complex distribution network. The investigation of a large outbreak of Escherichia coli O157 PT34 infection in the United Kingdom in 2016 indicated that catering venues associated with multiple cases had used salad leaves sourced from one supplier. Our aim was to investigate whether catering venues linked to cases were more likely to have used salad leaves from this supplier. We conducted a matched case–control study, with catering venues as the units of analysis. We compared venues linked to cases to those without known linked cases. We included 43 study pairs and obtained information on salad leaf products received by each venue. The odds of a case venue being supplied with salad leaves by Supplier A were 7.67 times (95% confidence interval: 2.30–25.53) those of control venues. This association provided statistical evidence to support the findings of the other epidemiological investigations undertaken for this outbreak. This is a novel approach which is labour-intensive but which addresses the challenge of investigating exposures to food across a complex distribution network.
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spelling pubmed-60536262018-08-29 Novel application of the matched case–control design to compare food supply chains during an Escherichia coli O157 outbreak, United Kingdom, 2016 Inns, Thomas Cleary, Paul Bundle, Nick Foulkes, Sarah Sharp, Ashley Utsi, Lara McBrien, Chris Teagle, Rehman Waldram, Alison Williams, Chris McCann, Cathy Smith, Rob Saleh, Sepeedeh McCarthy, Noel Vivancos, Roberto Hawker, Jeremy Decraene, Valerie Euro Surveill Surveillance and Outbreak Report There is a need for innovative methods to investigate outbreaks of food-borne infection linked to produce with a complex distribution network. The investigation of a large outbreak of Escherichia coli O157 PT34 infection in the United Kingdom in 2016 indicated that catering venues associated with multiple cases had used salad leaves sourced from one supplier. Our aim was to investigate whether catering venues linked to cases were more likely to have used salad leaves from this supplier. We conducted a matched case–control study, with catering venues as the units of analysis. We compared venues linked to cases to those without known linked cases. We included 43 study pairs and obtained information on salad leaf products received by each venue. The odds of a case venue being supplied with salad leaves by Supplier A were 7.67 times (95% confidence interval: 2.30–25.53) those of control venues. This association provided statistical evidence to support the findings of the other epidemiological investigations undertaken for this outbreak. This is a novel approach which is labour-intensive but which addresses the challenge of investigating exposures to food across a complex distribution network. European Centre for Disease Prevention and Control (ECDC) 2018-05-03 /pmc/articles/PMC6053626/ /pubmed/29741154 http://dx.doi.org/10.2807/1560-7917.ES.2018.23.18.17-00195 Text en This article is copyright of The Authors, 2018. http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution (CC BY 4.0) Licence. You may share and adapt the material, but must give appropriate credit to the source, provide a link to the licence, and indicate if changes were made.
spellingShingle Surveillance and Outbreak Report
Inns, Thomas
Cleary, Paul
Bundle, Nick
Foulkes, Sarah
Sharp, Ashley
Utsi, Lara
McBrien, Chris
Teagle, Rehman
Waldram, Alison
Williams, Chris
McCann, Cathy
Smith, Rob
Saleh, Sepeedeh
McCarthy, Noel
Vivancos, Roberto
Hawker, Jeremy
Decraene, Valerie
Novel application of the matched case–control design to compare food supply chains during an Escherichia coli O157 outbreak, United Kingdom, 2016
title Novel application of the matched case–control design to compare food supply chains during an Escherichia coli O157 outbreak, United Kingdom, 2016
title_full Novel application of the matched case–control design to compare food supply chains during an Escherichia coli O157 outbreak, United Kingdom, 2016
title_fullStr Novel application of the matched case–control design to compare food supply chains during an Escherichia coli O157 outbreak, United Kingdom, 2016
title_full_unstemmed Novel application of the matched case–control design to compare food supply chains during an Escherichia coli O157 outbreak, United Kingdom, 2016
title_short Novel application of the matched case–control design to compare food supply chains during an Escherichia coli O157 outbreak, United Kingdom, 2016
title_sort novel application of the matched case–control design to compare food supply chains during an escherichia coli o157 outbreak, united kingdom, 2016
topic Surveillance and Outbreak Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6053626/
https://www.ncbi.nlm.nih.gov/pubmed/29741154
http://dx.doi.org/10.2807/1560-7917.ES.2018.23.18.17-00195
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