Cargando…

GSK-3β, a double-edged sword in Nrf2 regulation: Implications for neurological dysfunction and disease

In the past decade, it has become evident that glycogen synthase kinase 3β (GSK-3β) modulates the nuclear factor erythroid 2-related factor 2 (Nrf2) oxidative stress response. GSK-3β functions as an inhibitor, both directly in the activation and indirectly in the post-induction of Nrf2. The incidenc...

Descripción completa

Detalles Bibliográficos
Autores principales: Culbreth, Megan, Aschner, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: F1000 Research Limited 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6053695/
https://www.ncbi.nlm.nih.gov/pubmed/30079246
http://dx.doi.org/10.12688/f1000research.15239.1