Cargando…

Distinct transcriptional responses of mouse sensory neurons in models of human chronic pain conditions

Background: Sensory neurons play an essential role in almost all pain conditions, and have recently been classified into distinct subsets on the basis of their transcriptomes. Here we have analysed alterations in dorsal root ganglia (DRG) gene expression using microarrays in mouse models related to...

Descripción completa

Detalles Bibliográficos
Autores principales:	Bangash, M.A., Alles, Sascha R.A., Santana-Varela, Sonia, Millet, Queensta, Sikandar, Shafaq, de Clauser, Larissa, ter Heegde, Freija, Habib, Abdella M., Pereira, Vanessa, Sexton, Jane E., Emery, Edward C., Li, Shengnan, Luiz, Ana P., Erdos, Janka, Gossage, Samuel J., Zhao, Jing, Cox, James J., Wood, John N.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	F1000 Research Limited 2018
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6053702/ https://www.ncbi.nlm.nih.gov/pubmed/30079380 http://dx.doi.org/10.12688/wellcomeopenres.14641.1

Ejemplares similares

Brain-derived neurotrophic factor derived from sensory neurons plays a critical role in chronic pain
por: Sikandar, Shafaq, et al.
Publicado: (2018)

Gate control of sensory neurotransmission in peripheral ganglia by proprioceptive sensory neurons
por: Fuller, Alice M, et al.
Publicado: (2023)

Physiologic osteoclasts are not sufficient to induce skeletal pain in mice
por: de Clauser, Larissa, et al.
Publicado: (2020)

Sensory neuron–derived Na(V)1.7 contributes to dorsal horn neuron excitability
por: Alles, Sascha R. A., et al.
Publicado: (2020)

Sensitization of Cutaneous Primary Afferents in Bone Cancer Revealed by In Vivo Calcium Imaging
por: de Clauser, Larissa, et al.
Publicado: (2020)

Tools for analysis and conditional deletion of subsets of sensory neurons
por: Santana-Varela, Sonia, et al.
Publicado: (2021)

Noninvasive Mechanical Joint Loading as an Alternative Model for Osteoarthritic Pain
por: ter Heegde, Freija, et al.
Publicado: (2019)

A central mechanism of analgesia in mice and humans lacking the sodium channel Na(V)1.7
por: MacDonald, Donald Iain, et al.
Publicado: (2021)

Development and evaluation of an escape room based on general pharmacokinetics: Students' perceptions of its motivational climate
por: van Houwelingen, Anneke, et al.
Publicado: (2023)

Cold sensing by Na(V)1.8-positive and Na(V)1.8-negative sensory neurons
por: Luiz, A. P., et al.
Publicado: (2019)

Chemogenetic Silencing of Na(V)1.8-Positive Sensory Neurons Reverses Chronic Neuropathic and Bone Cancer Pain in FLEx PSAM(4)-GlyR Mice
por: Haroun, Rayan, et al.
Publicado: (2023)

Pharmacological modulation of conditioned fear in the fear-potentiated startle test: a systematic review and meta-analysis of animal studies
por: Groenink, Lucianne, et al.
Publicado: (2023)

Activation of somatodendritic 5-HT(1A) autoreceptors reduces the acquisition and expression of cued fear in the rat fear-potentiated startle test
por: Zhao, Yulong, et al.
Publicado: (2018)

Endogenous opioids contribute to insensitivity to pain in humans and mice lacking sodium channel Na(v)1.7
por: Minett, Michael S., et al.
Publicado: (2015)

Sensory processing of deep tissue nociception in the rat spinal cord and thalamic ventrobasal complex
por: Sikandar, Shafaq, et al.
Publicado: (2017)

Silent cold-sensing neurons contribute to cold allodynia in neuropathic pain
por: MacDonald, Donald Iain, et al.
Publicado: (2021)

A novel human pain insensitivity disorder caused by a point mutation in ZFHX2
por: Habib, Abdella M, et al.
Publicado: (2018)

Pregabalin modulation of spinal and brainstem visceral nociceptive processing
por: Sikandar, Shafaq, et al.
Publicado: (2011)

In vivo characterization of distinct modality-specific subsets of somatosensory neurons using GCaMP
por: Emery, Edward C., et al.
Publicado: (2016)

Neutrophils infiltrate sensory ganglia and mediate chronic widespread pain in fibromyalgia
por: Caxaria, Sara, et al.
Publicado: (2023)

Effect of the spider toxin Tx3-3 on spinal processing of sensory information in naive and neuropathic rats: an in vivo electrophysiological study
por: Dalmolin, Gerusa D., et al.
Publicado: (2017)

Brainstem facilitations and descending serotonergic controls contribute to visceral nociception but not pregabalin analgesia in rats
por: Sikandar, Shafaq, et al.
Publicado: (2012)

The mechanisms and management of persistent postsurgical pain
por: Fuller, Alice M., et al.
Publicado: (2023)

Mechanisms of cancer pain
por: Haroun, Rayan, et al.
Publicado: (2023)

Transcriptomic and proteomic profiling of Na(V)1.8-expressing mouse nociceptors
por: Schmidt, Manuela, et al.
Publicado: (2022)

CCK2 receptors in chronic pain
por: LaVigne, Justin E., et al.
Publicado: (2022)

Pathogen recognition by sensory neurons: hypotheses on the specificity of sensory neuron signaling
por: Millet, Antoine, et al.
Publicado: (2023)

Putative roles of SLC7A5 (LAT1) transporter in pain
por: Alles, Sascha R.A., et al.
Publicado: (2020)

Analgesia linked to Nav1.7 loss of function requires µ- and δ-opioid receptors
por: Pereira, Vanessa, et al.
Publicado: (2018)

Plant-derived natural products targeting ion channels for pain
por: Goyal, Sachin, et al.
Publicado: (2023)

Microdeletion in a FAAH pseudogene identified in a patient with high anandamide concentrations and pain insensitivity
por: Habib, Abdella M., et al.
Publicado: (2019)

Mapping protein interactions of sodium channel Na(V)1.7 using epitope‐tagged gene‐targeted mice
por: Kanellopoulos, Alexandros H, et al.
Publicado: (2018)

Editorial: Insights in pain mechanisms 2022
por: Alles, Sascha R. A.
Publicado: (2023)

Fracture-induced pain-like behaviours in a femoral fracture mouse model
por: Magnusdottir, R., et al.
Publicado: (2021)

Genes, molecules and patients—Emerging topics to guide clinical pain research
por: Sikandar, Shafaq, et al.
Publicado: (2013)

Proteome and Network Analysis Provides Novel Insights Into Developing and Established Chemotherapy-Induced Peripheral Neuropathy
por: de Clauser, Larissa, et al.
Publicado: (2022)

Pain-related behavioral and electrophysiological actions of dynorphin A (1-17)
por: LaVigne, Justin E, et al.
Publicado: (2023)

The effects of modulatory systems in sensory thalamic nuclei
por: Varela, Carmen, et al.
Publicado: (2007)

Peripheral Voltage-Gated Cation Channels in Neuropathic Pain and Their Potential as Therapeutic Targets
por: Alles, Sascha R. A., et al.
Publicado: (2021)

Characterization of the mono-s di-Higgs signal in ﬁnal states with four b-jets and missing transverse momentum
por: Beirnaert, Freija Femke J
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_n4ekafitdc9an35ke4ufv162lk