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Resibufogenin suppresses colorectal cancer growth and metastasis through RIP3-mediated necroptosis

BACKGROUND: Necroptotic susceptibility is probably an intrinsic weakness of cancer. Here, we report that resibufogenin, a member of bufadienolide family, suppresses the growth and metastasis of colorectal cancer (CRC) through induction of necroptosis in vivo. METHODS: SW480 cells with stably express...

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Detalles Bibliográficos
Autores principales:	Han, Qinrui, Ma, Ye, Wang, Hao, Dai, Yu, Chen, Chunhui, Liu, Yawei, Jing, Linlin, Sun, Xuegang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2018
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6053767/ https://www.ncbi.nlm.nih.gov/pubmed/30029665 http://dx.doi.org/10.1186/s12967-018-1580-x

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