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Functional and genomic analyses reveal therapeutic potential of targeting β-catenin/CBP activity in head and neck cancer

BACKGROUND: Head and neck squamous cell carcinoma (HNSCC) is an aggressive malignancy characterized by tumor heterogeneity, locoregional metastases, and resistance to existing treatments. Although a number of genomic and molecular alterations associated with HNSCC have been identified, they have had...

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Detalles Bibliográficos
Autores principales:	Kartha, Vinay K., Alamoud, Khalid A., Sadykov, Khikmet, Nguyen, Bach-Cuc, Laroche, Fabrice, Feng, Hui, Lee, Jina, Pai, Sara I., Varelas, Xaralabos, Egloff, Ann Marie, Snyder-Cappione, Jennifer E., Belkina, Anna C., Bais, Manish V., Monti, Stefano, Kukuruzinska, Maria A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2018
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6053793/ https://www.ncbi.nlm.nih.gov/pubmed/30029671 http://dx.doi.org/10.1186/s13073-018-0569-7

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