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Immortal Time Bias in Observational Studies of Time-to-Event Outcomes: Assessing Effects of Postmastectomy Radiation Therapy Using the National Cancer Database
The objectives of this study are to illustrate the effects of immortal time bias (ITB) using an oncology outcomes database and quantify through simulations the magnitude and direction of ITB when different analytical techniques are used. A cohort of 11 626 women who received neoadjuvant chemotherapy...
Autores principales: | Agarwal, Parul, Moshier, Erin, Ru, Meng, Ohri, Nisha, Ennis, Ronald, Rosenzweig, Kenneth, Mazumdar, Madhu |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
SAGE Publications
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6053873/ https://www.ncbi.nlm.nih.gov/pubmed/30021466 http://dx.doi.org/10.1177/1073274818789355 |
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