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Applications of the class II lanthipeptide protease LicP for sequence-specific, traceless peptide bond cleavage
The final step of lanthipeptide biosynthesis involves the removal of leader peptides by dedicated proteases. In vitro characterization of LicP, a class II LanP protease involved in the biosynthesis of the lantibiotic lichenicidin, revealed a self-cleavage step that removes 100 amino acids from the N...
Autores principales: | Tang, Weixin, Dong, Shi-Hui, Repka, Lindsay M., He, Chang, Nair, Satish K., van der Donk, Wilfred A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Royal Society of Chemistry
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6054071/ https://www.ncbi.nlm.nih.gov/pubmed/30090246 http://dx.doi.org/10.1039/c5sc02329g |
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