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Making the longest sugars: a chemical synthesis of heparin-related [4](n) oligosaccharides from 16-mer to 40-mer

The chemical synthesis of long oligosaccharides remains a major challenge. In particular, the synthesis of glycosaminoglycan (GAG) oligosaccharides belonging to the heparin and heparan sulfate (H/HS) family has been a high profile target, particularly with respect to the longer heparanome. Herein we...

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Detalles Bibliográficos
Autores principales: Hansen, Steen U., Miller, Gavin J., Cliff, Matthew J., Jayson, Gordon C., Gardiner, John M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Royal Society of Chemistry 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6054106/
https://www.ncbi.nlm.nih.gov/pubmed/30090231
http://dx.doi.org/10.1039/c5sc02091c