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Nitrite circumvents platelet resistance to nitric oxide in patients with heart failure preserved ejection fraction and chronic atrial fibrillation
AIMS: Heart failure (HF) is a pro-thrombotic state. Both platelet and vascular responses to nitric oxide (NO) donors are impaired in HF patients with reduced ejection fraction (HFrEF) compared with healthy volunteers (HVs) due to scavenging of NO, and possibly also reduced activity of the principal...
Autores principales: | Borgognone, Alessandra, Shantsila, Eduard, Worrall, Sophie M, Prompunt, Eakkapote, Loka, Thomas, Loudon, Brodie L, Chimen, Myriam, Ed Rainger, G, Lord, Janet M, Turner, Ashley, Nightingale, Peter, Feelisch, Martin, Kirchhof, Paulus, Lip, Gregory Y H, Watson, Steve P, Frenneaux, Michael P, Madhani, Melanie |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6054254/ https://www.ncbi.nlm.nih.gov/pubmed/29659727 http://dx.doi.org/10.1093/cvr/cvy087 |
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