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Nitrite circumvents platelet resistance to nitric oxide in patients with heart failure preserved ejection fraction and chronic atrial fibrillation

AIMS: Heart failure (HF) is a pro-thrombotic state. Both platelet and vascular responses to nitric oxide (NO) donors are impaired in HF patients with reduced ejection fraction (HFrEF) compared with healthy volunteers (HVs) due to scavenging of NO, and possibly also reduced activity of the principal...

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Detalles Bibliográficos
Autores principales: Borgognone, Alessandra, Shantsila, Eduard, Worrall, Sophie M, Prompunt, Eakkapote, Loka, Thomas, Loudon, Brodie L, Chimen, Myriam, Ed Rainger, G, Lord, Janet M, Turner, Ashley, Nightingale, Peter, Feelisch, Martin, Kirchhof, Paulus, Lip, Gregory Y H, Watson, Steve P, Frenneaux, Michael P, Madhani, Melanie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6054254/
https://www.ncbi.nlm.nih.gov/pubmed/29659727
http://dx.doi.org/10.1093/cvr/cvy087

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