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Genomic Rearrangement Signatures and Clinical Outcomes in High-Grade Serous Ovarian Cancer

BACKGROUND: To identify clinically relevant genomic rearrangement signatures in high-grade serous ovarian cancer (HGSOC), we conducted a retrospective analysis of sequenced HGSOC whole-tumor genomes. METHODS: Clinical data and whole-genome sequencing (WGS) reads were obtained for primary HGSOC tumor...

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Detalles Bibliográficos
Autores principales:	Hillman, R Tyler, Chisholm, Gary B, Lu, Karen H, Futreal, P Andrew
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2017
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6054271/ https://www.ncbi.nlm.nih.gov/pubmed/29584920 http://dx.doi.org/10.1093/jnci/djx176

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